Single cells proliferate to form colonies that can then be assessed for.
Cell line development workflow.
Cell line development cld on the beacon optofluidic system enables selection of the best production cell lines with 99 monoclonality assurance in just days.
Interested in rapid and efficient stable cell pool cell line development for large scale production of your recombinant antibodies and proteins.
Cell line development is the process of establishing a clonally derived cell population which has been genetically engineered to express a desirable phenotype such as producing large amounts of recombinant protein for a stable period of time.
For the greatest genetic diversity you need to screen thousands of cells.
Solentim technology streamlines workflows in the creation isolation and characterization of high value cells in cell line development vaccine production cell and gene therapy.
The opto cld workflow screens thousands of clones with ease in less than a week.
From vector design and host cell selection prior to transfection single cell cloning and colony outgrowth right through to the establishment of the master cell bank solentim technologies provide the evidence for.
The new opto cld 2 0 workflow extends these capabilities to allow 1 enrichment of rare cell populations 2 on chip titer measurements for traditional and non traditional antibody molecules and 3 efficient recovery.
Cell line development campaigns are typically performed over the course of several weeks to months at a time.
In cell line development cld you are looking for the rare high producing clones.
We accelerate cell line workflow timelines from upstream development through scale up to production of new biological therapies.
This innovative offering is based on uga s well established platform technologies including their proprietary cho host cell lines system optimized expression vectors and.
In the case of monoclonal antibody production the process of developing stable cell lines starts with transfecting host cells with recombinant plasmid dna encoding the.
Cell line development workflow in order to generate high yields of recombinant protein products stable cell lines such as cho or hek 293 are typical vehicles of choice.
The uga biopharma gmbh high speed workflow was established as an improved cell line development workflow that guarantees cho cell line development on a shortened time scale.
